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- _5 label "Selventa" provenance.
- _3 title "Landes Bioscience - Altered Integrin Expression in Three Common Types of Human Cancer=Breast Cancer" provenance.
- large_corpus.bel title "BEL Framework Large Corpus Document" provenance.
- _3 type "Other" provenance.
- _3 identifier "Landes Bioscience - Altered Integrin Expression in Three Common Types of Human Cancer=Breast Cancer" provenance.
- large_corpus.bel description "Approximately 61,000 statements." provenance.
- large_corpus.bel version "1.4" provenance.
- large_corpus.bel authoredBy _5 provenance.
- assertion wasDerivedFrom _4 provenance.
- assertion wasDerivedFrom large_corpus.bel provenance.
- assertion hadPrimarySource _3 provenance.
- _4 wasQuotedFrom _3 provenance.
- _4 value "Furthermore, epidermal growth factor and its receptor (EGFR), as well as the breast cancer-related protein ERBB-2, have been reported to mediate up-regulation of b1 integrin function and breast cancer progression. Activation of PI3-kinase plays a role in the signalling of both of these receptors. 74 It has also been suggested that the overexpression of breast cancer-related protein ERBB-2 may induce fibronectin-dependent invasion with concomitant down-regulation of a4 integrin cell surface expression. 75" provenance.
- large_corpus.bel rights "Copyright (c) 2011-2012, Selventa. All rights reserved." provenance.