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- _6 label "Selventa" provenance.
- large_corpus.bel title "BEL Framework Large Corpus Document" provenance.
- large_corpus.bel description "Approximately 61,000 statements." provenance.
- large_corpus.bel version "20131211" provenance.
- large_corpus.bel authoredBy _6 provenance.
- assertion wasDerivedFrom large_corpus.bel provenance.
- assertion wasDerivedFrom _5 provenance.
- assertion hadPrimarySource 11841347 provenance.
- _5 wasQuotedFrom 11841347 provenance.
- _5 value "The main role of uPA in extracellular proteolysis is a generation of cell surface associated plasmin cleaving the main components of the basement membrane and of the extracellular matrix and activating matrix metalloproteinases, which degrade the components resistant to plasmin [1, 3, 42]. Essential for the proteolytic function of uPA is its ability to directly or via plasmin production activate latent or release matrix-bound growth factors. Thus, uPA itself proteolytically activates proforms of hepatocyte growth factor (HGF), of macrophage-stimulating protein (MSP), and of an isoform of vascular endothelial growth factor (VEGF189) [43, 44]." provenance.
- large_corpus.bel rights "Copyright (c) 2011-2012, Selventa. All rights reserved." provenance.