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- _8 label "Selventa" provenance.
- large_corpus.bel title "BEL Framework Large Corpus Document" provenance.
- large_corpus.bel description "Approximately 61,000 statements." provenance.
- large_corpus.bel version "20131211" provenance.
- large_corpus.bel authoredBy _8 provenance.
- assertion wasDerivedFrom large_corpus.bel provenance.
- assertion wasDerivedFrom _7 provenance.
- assertion hadPrimarySource 17052212 provenance.
- _7 wasQuotedFrom 17052212 provenance.
- _7 value "CAPRI-knockout mouse. Cells from this animal have the predicted hyperactivation of Ras signalling, which is consistent with the loss of an important Ras-GAP. Interestingly, Zhang et al. [40] also noted a decrease in the activation of the small GTPases Rac and Cdc42. This effect appeared not to arise through the hyperactivation of Ras, nor was it a consequence of CAPRI functioning as a Cdc42/Rac GEF, rather the authors show that CAPRI, via its Ras-GAP domain, can bind Rac and Cdc42 directly and act as a scaffold for presenting these GTPases to an unidentified GEF. " provenance.
- large_corpus.bel rights "Copyright (c) 2011-2012, Selventa. All rights reserved." provenance.