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- _7 label "Selventa" provenance.
- _7 comment "support@belframework.org" provenance.
- small_corpus.bel title "BEL Framework Small Corpus Document" provenance.
- small_corpus.bel description "Approximately 2000 hand curated statements drawn from 57 PubMeds." provenance.
- small_corpus.bel version "20131211" provenance.
- small_corpus.bel authoredBy _7 provenance.
- assertion wasDerivedFrom small_corpus.bel provenance.
- assertion wasDerivedFrom _6 provenance.
- assertion hadPrimarySource 12764228 provenance.
- _6 wasQuotedFrom 12764228 provenance.
- _6 value "Real-time PCR primers were designed for the PGC-1α 3' untranslated region that allows for determination of the levels of ectopically expressed and endogenous PGC-1α. As shown in Fig. 4B and as expected, ectopic PGC-1α is detected only in the muscle of transgenic mice. Strikingly, a 7-fold elevation of endogenous PGC-1α mRNA was seen in the transgenic animals as compared with wild-type mice (Fig. 4B). A robust increase in the transcript levels of cytochrome c and myoglobin also was observed in the RNA isolated from skeletal muscle of the transgenic mice, whereas GAPDH transcript levels remained unchanged (Fig. 4B). These results indicate a regulation of PGC-1α transcription by PGC-1α protein in an apparent autoregulatory loop." provenance.
- small_corpus.bel license "Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License" provenance.
- small_corpus.bel rights "Copyright (c) 2011-2012, Selventa. All Rights Reserved." provenance.