Matches in Nanopublications for { ?s ?p ?o <http://www.tkuhn.ch/bel2nanopub/RAeVUB8u4um26m32FA3Bb-LzCPcj4FBKhobhJZ_KOzhtg#provenance>. }
Showing items 1 to 13 of
13
with 100 items per page.
- _9 label "Selventa" provenance.
- _9 comment "support@belframework.org" provenance.
- small_corpus.bel title "BEL Framework Small Corpus Document" provenance.
- small_corpus.bel description "Approximately 2000 hand curated statements drawn from 57 PubMeds." provenance.
- small_corpus.bel version "20131211" provenance.
- small_corpus.bel authoredBy _9 provenance.
- assertion wasDerivedFrom small_corpus.bel provenance.
- assertion wasDerivedFrom _8 provenance.
- assertion hadPrimarySource 16170185 provenance.
- _8 wasQuotedFrom 16170185 provenance.
- _8 value "The activation of B-Raf by Ras has been less well studied; however, the interacting amino acids in the Ras-Raf interface are identical for B-Raf and C-Raf.129,130 The association of Ras with B-Raf also translocates B-Raf to the cell membrane where it is activated.124 Interestingly, a membrane-free complex of B-Raf and 14-3-3 can be activated in vitro by recombinant Ras. This is in stark contrast to A-Raf and C-Raf, which must undergo a series of phosphorylation reactions on serine and tyrosine residues in the cell membrane and cannot be activated by Ras alone.124,130 Of the Raf isoforms, B-Raf is activated first, and on stimulation by Ras, it heterodimerizes with C-Raf, the significance of which is not known.94" provenance.
- small_corpus.bel license "Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License" provenance.
- small_corpus.bel rights "Copyright (c) 2011-2012, Selventa. All Rights Reserved." provenance.