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- _4 label "Selventa" provenance.
- large_corpus.bel title "BEL Framework Large Corpus Document" provenance.
- large_corpus.bel description "Approximately 61,000 statements." provenance.
- large_corpus.bel version "1.4" provenance.
- large_corpus.bel authoredBy _4 provenance.
- assertion wasDerivedFrom large_corpus.bel provenance.
- assertion wasDerivedFrom _3 provenance.
- assertion hadPrimarySource 11215509 provenance.
- _3 wasQuotedFrom 11215509 provenance.
- _3 value "Overexpressed Gpx4 approximately threefold, the conversion of arachidonic acid to intermediates in the lipoxygenase pathway was inhibited eightfold (leukotriene C4 and leukotriene B4). Normal rates of leukotriene C4 formation were restored in the transfected cell by treatment with the inhibitor diethylmalate, which decreases GPX4 activity...The authors concluded that Gpx4 deactivated 5-lipoxygenase via decreases in levels of hydroperoxides required for activation of the enzyme." provenance.
- large_corpus.bel rights "Copyright (c) 2011-2012, Selventa. All rights reserved." provenance.