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- _6 label "Selventa" provenance.
- large_corpus.bel title "BEL Framework Large Corpus Document" provenance.
- large_corpus.bel description "Approximately 61,000 statements." provenance.
- large_corpus.bel version "20131211" provenance.
- large_corpus.bel authoredBy _6 provenance.
- assertion wasDerivedFrom large_corpus.bel provenance.
- assertion wasDerivedFrom _5 provenance.
- assertion hadPrimarySource 13130303 provenance.
- _5 wasQuotedFrom 13130303 provenance.
- _5 value "Several growth factors, most notably insulin-like growth factor-2 (IGF2) and transforming growth factor-a (TGF-a), are also HIF-1 target genes. Binding of these factors to their cognate receptors the insulin-like growth factor 1 receptor (IGF1R) and epidermal growth-factor receptor (EGFR), respectively activates signal-transduction pathways that lead both to HIF-1a expression (as described above) and to cell proliferation survival. HIF-1 therefore contributes to autocrine-signalling pathways that are crucial for cancer progression (FIG. 6)." provenance.
- large_corpus.bel rights "Copyright (c) 2011-2012, Selventa. All rights reserved." provenance.