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- _6 label "Selventa" provenance.
- large_corpus.bel title "BEL Framework Large Corpus Document" provenance.
- large_corpus.bel description "Approximately 61,000 statements." provenance.
- large_corpus.bel version "20131211" provenance.
- large_corpus.bel authoredBy _6 provenance.
- assertion wasDerivedFrom large_corpus.bel provenance.
- assertion wasDerivedFrom _5 provenance.
- assertion hadPrimarySource 17157248 provenance.
- _5 wasQuotedFrom 17157248 provenance.
- _5 value "(Shenoy et al., 2001). Ubiquitination is triggered by interaction of b-arrestin with an activated receptor and is catalyzed by the RING finger E3 ligase MDM2, which binds b-arrestin...Not only are b-arrestins themselves ubiquitinated, but b-arrestins can also serve as adaptors to bring E3 ligases into proximity with receptors... This has been shown for the d opioid receptor (Wang et al., 2003) and the IGF1 receptor tyrosine kinase, the latter having been shown to be ubiquitinated by MDM2, leading to its proteasomal destruction (Girnita et al., 2005)." provenance.
- large_corpus.bel rights "Copyright (c) 2011-2012, Selventa. All rights reserved." provenance.