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- _5 label "Selventa" provenance.
- large_corpus.bel title "BEL Framework Large Corpus Document" provenance.
- large_corpus.bel description "Approximately 61,000 statements." provenance.
- large_corpus.bel version "20131211" provenance.
- large_corpus.bel authoredBy _5 provenance.
- assertion wasDerivedFrom large_corpus.bel provenance.
- assertion wasDerivedFrom _4 provenance.
- assertion hadPrimarySource 15489897 provenance.
- _4 wasQuotedFrom 15489897 provenance.
- _4 value "Stimulation of PKCs in U-251 cells for 30 min with 100 nM PMA, showed an increased phosphorylation of mTOR at ser-2448 by 43+/-10-fold compared with untreated cells. Expression of PKC-etaKR, a kinase dead mutant of PKCeta significantly reduced PMA stimulated ser-2448 phosphorylation of mTOR by 54+/-12%. In U-1242 PKCdeltaNPS, a catalytically active PKC expression increased phosphorylation on ser-2448 of mTOR by 322+/-58% as compared to the empty vector, suggesting that PKCeta activates mTOR." provenance.
- large_corpus.bel rights "Copyright (c) 2011-2012, Selventa. All rights reserved." provenance.