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- _7 label "Selventa" provenance.
- large_corpus.bel title "BEL Framework Large Corpus Document" provenance.
- large_corpus.bel description "Approximately 61,000 statements." provenance.
- large_corpus.bel version "1.4" provenance.
- large_corpus.bel authoredBy _7 provenance.
- assertion wasDerivedFrom large_corpus.bel provenance.
- assertion wasDerivedFrom _6 provenance.
- assertion hadPrimarySource 13130303 provenance.
- _6 wasQuotedFrom 13130303 provenance.
- _6 value "studies of MCF-7 breast cancer cells stimulated with heregulin showed increased HIF-1a protein synthesis that was inhibited by treatment with rapamycin a macrolide antibiotic that inhibits mammalian target of rapamycin (mTOR; a kinase that functions downstream of PI3K and AKT). The effect of heregulin was mediated via the 5-untranslated region of HIF-1a mRNA47. The known targets for phosphorylation by mTOR are regulators of protein synthesis (FIG. 1)." provenance.
- large_corpus.bel rights "Copyright (c) 2011-2012, Selventa. All rights reserved." provenance.