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- _4 label "Selventa" provenance.
- large_corpus.bel title "BEL Framework Large Corpus Document" provenance.
- large_corpus.bel description "Approximately 61,000 statements." provenance.
- large_corpus.bel version "20131211" provenance.
- large_corpus.bel authoredBy _4 provenance.
- assertion wasDerivedFrom large_corpus.bel provenance.
- assertion wasDerivedFrom _3 provenance.
- assertion hadPrimarySource 10446999 provenance.
- _3 wasQuotedFrom 10446999 provenance.
- _3 value "To monitor the ability of ATRA and VD to activate the genetic program underlying monocytic differentiation in the M2 cellular context, we have investigated the expression of VD-responsive genes (Fig. 8) such as HMSE-1, CD14, and hOC by RT-PCR and the expression of genes controlled by a functional VDRE, such as p21waf-1 (51) , or RARE, such as E3 (52) , IRF-1 (53) and p21waf-1 (68) , by Northern blot analysis after different times of ATRA or VD treatment. Fig. 8 shows that both ATRA and VD treatment of Kasumi-1 cells causes a rapid induction of HMSE-1, CD14, and hOC expression, demonstrating VDR involvement in ATRA-dependent monocytic differentiation of M2-type blast cells." provenance.
- large_corpus.bel rights "Copyright (c) 2011-2012, Selventa. All rights reserved." provenance.