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- _6 label "Selventa" provenance.
- large_corpus.bel title "BEL Framework Large Corpus Document" provenance.
- large_corpus.bel description "Approximately 61,000 statements." provenance.
- large_corpus.bel version "20131211" provenance.
- large_corpus.bel authoredBy _6 provenance.
- assertion wasDerivedFrom large_corpus.bel provenance.
- assertion wasDerivedFrom _5 provenance.
- assertion hadPrimarySource 11016663 provenance.
- _5 wasQuotedFrom 11016663 provenance.
- _5 value "80 nM wortmannin reduced both ET-1 and EGF-induced Erk 2 activation. Quantitative densitometric analysis indicated that wortmannin caused a 32% reduction in the phosphorylated:unphosphorylated Erk 2 ratio in ET-1-stimulated cells. ET-1-induced Erk 2 phosphorylation was only partially blocked in the presence of both inhibitors. The degree of inhibition (36%) was similar to that caused by tryphostin AG1478 or wortmannin alone. These results indicate that the tryphostin AG1478-insensitive activation of Erk2 is only partially attributable to the contribution of a PI3K-dependent pathway." provenance.
- large_corpus.bel rights "Copyright (c) 2011-2012, Selventa. All rights reserved." provenance.