Matches in Nanopublications for { ?s ?p "Overexpressed Gpx4 approximately threefold, the conversion of arachidonic acid to intermediates in the lipoxygenase pathway was inhibited eightfold (leukotriene C4 and leukotriene B4). Normal rates of leukotriene C4 formation were restored in the transfected cell by treatment with the inhibitor diethylmalate, which decreases GPX4 activity...The authors concluded that Gpx4 deactivated 5-lipoxygenase via decreases in levels of hydroperoxides required for activation of the enzyme." ?g. }
Showing items 1 to 2 of
2
with 100 items per page.
- _3 value "Overexpressed Gpx4 approximately threefold, the conversion of arachidonic acid to intermediates in the lipoxygenase pathway was inhibited eightfold (leukotriene C4 and leukotriene B4). Normal rates of leukotriene C4 formation were restored in the transfected cell by treatment with the inhibitor diethylmalate, which decreases GPX4 activity...The authors concluded that Gpx4 deactivated 5-lipoxygenase via decreases in levels of hydroperoxides required for activation of the enzyme." provenance.
- _3 value "Overexpressed Gpx4 approximately threefold, the conversion of arachidonic acid to intermediates in the lipoxygenase pathway was inhibited eightfold (leukotriene C4 and leukotriene B4). Normal rates of leukotriene C4 formation were restored in the transfected cell by treatment with the inhibitor diethylmalate, which decreases GPX4 activity...The authors concluded that Gpx4 deactivated 5-lipoxygenase via decreases in levels of hydroperoxides required for activation of the enzyme." provenance.