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- drugbank:DB00398 type drugbank_vocabulary:Drug assertion.
- drugbank:DB00398 label "Sorafenib [drugbank:DB00398]" assertion.
- drugbank:DB00398 seeAlso nexavar-drug.htm assertion.
- drugbank:DB00398 seeAlso sorafenib.html assertion.
- drugbank:DB00398 seeAlso DB00398 assertion.
- drugbank:DB00398 description "Sorafenib (rINN), marketed as Nexavar by Bayer, is a drug approved for the treatment of advanced renal cell carcinoma (primary kidney cancer). It has also received "Fast Track" designation by the FDA for the treatment of advanced hepatocellular carcinoma (primary liver cancer), and has since performed well in Phase III trials. Sorafenib is a small molecular inhibitor of Raf kinase, PDGF (platelet-derived growth factor), VEGF receptor 2 & 3 kinases and c Kit the receptor for Stem cell factor. A growing number of drugs target most of these pathways. The originality of Sorafenib lays in its simultaneous targeting of the Raf/Mek/Erk pathway." assertion.
- drugbank:DB00398 identifier "drugbank:DB00398" assertion.
- drugbank:DB00398 title "Sorafenib" assertion.
- drugbank:DB00398 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00072_DB00398 assertion.
- drugbank:DB00398 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00398_DB00755 assertion.
- drugbank:DB00398 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00398_DB00958 assertion.
- drugbank:DB00398 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00398_DB06414 assertion.
- drugbank:DB00398 drugbank_vocabulary:x-pubchemsubstance pubchem.substance:46505329 assertion.
- drugbank:DB00398 drugbank_vocabulary:x-pubchemcompound pubchem.compound:216239 assertion.
- drugbank:DB00398 drugbank_vocabulary:x-pdb pdb:BAX assertion.
- drugbank:DB00398 drugbank_vocabulary:x-chemspider chemspider:187440 assertion.
- drugbank:DB00398 drugbank_vocabulary:x-cas cas:284461-73-0 assertion.
- drugbank:DB00398 drugbank_vocabulary:drugbank-id "APRD01304" assertion.
- drugbank:DB00398 drugbank_vocabulary:drugbank-id "DB00398" assertion.
- drugbank:DB00398 drugbank_vocabulary:drugbank-id "DB07438" assertion.
- drugbank:DB00398 bio2rdf_vocabulary:x-identifiers.org DB00398 assertion.
- drugbank:DB00398 bio2rdf_vocabulary:uri "http://bio2rdf.org/drugbank:DB00398" assertion.
- drugbank:DB00398 bio2rdf_vocabulary:namespace "drugbank" assertion.
- drugbank:DB00398 bio2rdf_vocabulary:identifier "DB00398" assertion.
- drugbank:DB00398 drugbank_vocabulary:x-wikipedia wikipedia:Sorafenib assertion.
- drugbank:DB00398 drugbank_vocabulary:x-pharmgkb pharmgkb:PA7000 assertion.
- drugbank:DB00398 drugbank_vocabulary:x-kegg kegg:D08524 assertion.
- drugbank:DB00398 drugbank_vocabulary:x-chebi chebi:50924 assertion.
- drugbank:DB00398 drugbank_vocabulary:x-atc atc:L01XE05 assertion.
- drugbank:DB00398 drugbank_vocabulary:x-ahfs ahfs:92:00.00 assertion.
- drugbank:DB00398 drugbank_vocabulary:x-bindingdb bindingdb:16673 assertion.
- drugbank:DB00398 drugbank_vocabulary:x-ndc ndc:50419-488-58 assertion.