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Matches in Nanopublications for { <http://bio2rdf.org/drugbank:DB00472> ?p ?o ?g. }

• drugbank:DB00472 type drugbank_vocabulary:Drug assertion.
• drugbank:DB00472 label "Fluoxetine [drugbank:DB00472]" assertion.
• drugbank:DB00472 seeAlso fluoxetine.htm assertion.
• drugbank:DB00472 seeAlso fluoxetine.html assertion.
• drugbank:DB00472 seeAlso DB00472 assertion.
• drugbank:DB00472 description "Fluoxetine hydrochloride is the first agent of the class of antidepressants known as selective serotonin-reuptake inhibitors (SSRIs). Fluoxetine is a racemic mixture of the R- and S- enantiomers and are of equivalent pharmacologic activity. Despite distinct structural differences between compounds in this class, SSRIs possess similar pharmacological activity. As with other antidepressant agents, several weeks of therapy may be required before a clinical effect is seen. SSRIs are potent inhibitors of neuronal serotonin reuptake. They have little to no effect on norepinephrine or dopamine reuptake and do not antagonize α- or β-adrenergic, dopamine D₂ or histamine H₁ receptors. During acute use, SSRIs block serotonin reuptake and increase serotonin stimulation of somatodendritic 5-HT_1A and terminal autoreceptors. Chronic use leads to desensitization of somatodendritic 5-HT_1A and terminal autoreceptors. The overall clinical effect of increased mood and decreased anxiety is thought to be due to adaptive changes in neuronal function that leads to enhanced serotonergic neurotransmission. Side effects include dry mouth, nausea, dizziness, drowsiness, sexual dysfunction and headache. Side effects generally occur within the first two weeks of therapy and are usually less severe and frequent than those observed with tricyclic antidepressants. Fluoxetine may be used to treat major depressive disorder (MDD), moderate to severe bulimia nervosa, obsessive-compulsive disorder (OCD), premenstrual dysphoric disorder (PMDD), panic disorder with or without agoraphobia, and in combination with olanzapine for treatment-resistant or bipolar I depression. Fluoxetine is the most anorexic and stimulating SSRI." assertion.
• drugbank:DB00472 identifier "drugbank:DB00472" assertion.
• drugbank:DB00472 title "Fluoxetine" assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB00918 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00363_DB00472 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB00857 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00252_DB00472 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00321_DB00472 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB06697 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB00752 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB00497 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB00726 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00289_DB00472 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB00571 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB00697 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00191_DB00472 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB00952 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00199_DB00472 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB01418 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB00734 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00374_DB00472 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB00540 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB00637 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB00937 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB01600 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB00656 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB01320 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB01361 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB00682 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB00953 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB00933 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB00998 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB06708 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB00780 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB01166 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00182_DB00472 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB00675 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00382_DB00472 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB00579 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB01624 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00046_DB00472 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00246_DB00472 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB00514 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00427_DB00472 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB01171 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00264_DB00472 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB01576 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB01623 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB01577 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB00582 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB01579 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00266_DB00472 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB04946 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB01242 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB01036 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB01142 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB01009 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB01182 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB00564 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB00696 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB04844 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB01125 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB01367 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB00601 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB01211 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00091_DB00472 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00434_DB00472 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB01124 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00458_DB00472 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00344_DB00472 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00216_DB00472 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00285_DB00472 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB00543 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB00679 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB01247 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00397_DB00472 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB01323 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00315_DB00472 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB00503 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB02546 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB00865 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB00574 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB00532 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB00754 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB00864 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB01151 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00193_DB00472 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00342_DB00472 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB00932 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB08920 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB00500 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB01136 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB01321 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB01191 assertion.
• drugbank:DB00472 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00472_DB01381 assertion.

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