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- drugbank:DB01272 type drugbank_vocabulary:Drug assertion.
- drugbank:DB01272 label "Alglucosidase alfa [drugbank:DB01272]" assertion.
- drugbank:DB01272 seeAlso myozyme.htm assertion.
- drugbank:DB01272 seeAlso alglucosidase-alfa.html assertion.
- drugbank:DB01272 seeAlso DB01272 assertion.
- drugbank:DB01272 description "Aglucosidase alfa consists of the human enzyme acid alpha-glucosidase (GAA) which is essential for the degradation of glygogen to glucose in lysosomes. It is encoded by the most predominant of nine observed haplotypes of this gene. Aglucosidase alfa is produced by recombinant DNA technology in a Chinese hamster ovary cell line. Alglucosidase alfa degrades glycogen by catalyzing the hydrolysis of a-1,4- and a-1,6- glycosidic linkages of lysosomal glycogen. Structurally, Alglucosidase alfa is a glycoprotein with a calculated mass of 98,008 daltons for the 883 residue mature polypeptide chain, and a total mass of approximately 109,000 daltons, including carbohydrates. It is used for the treatment of Pompe disease (GAA deficiency) in infants and pediatric patients." assertion.
- drugbank:DB01272 identifier "drugbank:DB01272" assertion.
- drugbank:DB01272 title "Alglucosidase alfa" assertion.
- drugbank:DB01272 drugbank_vocabulary:x-cas cas:420784-05-0 assertion.
- drugbank:DB01272 drugbank_vocabulary:drugbank-id "DB01272" assertion.
- drugbank:DB01272 bio2rdf_vocabulary:x-identifiers.org DB01272 assertion.
- drugbank:DB01272 bio2rdf_vocabulary:uri "http://bio2rdf.org/drugbank:DB01272" assertion.
- drugbank:DB01272 bio2rdf_vocabulary:namespace "drugbank" assertion.
- drugbank:DB01272 bio2rdf_vocabulary:identifier "DB01272" assertion.
- drugbank:DB01272 drugbank_vocabulary:x-wikipedia wikipedia:Alglucosidase_alfa assertion.
- drugbank:DB01272 drugbank_vocabulary:x-pharmgkb pharmgkb:PA164754753 assertion.
- drugbank:DB01272 drugbank_vocabulary:x-kegg kegg:D03207 assertion.
- drugbank:DB01272 drugbank_vocabulary:x-dpd dpd:2284863 assertion.
- drugbank:DB01272 drugbank_vocabulary:x-atc atc:A16AB07 assertion.
- drugbank:DB01272 drugbank_vocabulary:x-ahfs ahfs:44:00.00 assertion.
- drugbank:DB01272 drugbank_vocabulary:x-ndc ndc:58468-0150-1 assertion.