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- drugbank:DB01546 type drugbank_vocabulary:Drug assertion.
- drugbank:DB01546 label "Alpha-ethyltryptamine [drugbank:DB01546]" assertion.
- drugbank:DB01546 seeAlso DB01546 assertion.
- drugbank:DB01546 description "In the 1960's, alpha-ethyltryptamine (αET), a non hydrazine reversible monoamine oxidase inhibitor, was developed in the United States by the Upjohn chemical company for use as an antidepressant. αET was an FDA approved antidepressant under the name Monase. However, in 1962, after the discovery of an unacceptable incidence of agranulocytosis, the development of Monase was halted and the drug was withdrawn from potential market use. In 1993, the US Drug Enforcement Administration added αET to Schedule I of its Schedules of Controlled Substances, after an increasing incidence of its use as a recreational drug in the 1980's. Currently, αET is an illegal substance; however, it's activity is still under scientific investigation. αET is a stimulant and hallucinogen, but it is less stimulating and hallucinogenic than alpha-methyltryptamine, a closely related compound. Instead, the effects of αET, a tryptamine derivative, more closely resemble the amphetamine derived drug 3,4-methylenedioxy-N-methylamphetamine (MDMA). Similarly to MDMA, αET has been shown to release serotonin pre-synaptically, as well as lesser amounts of norepinephrine and dopamine. Like MDMA, increases in locomotor activity and mood elevation can be seen post administration." assertion.
- drugbank:DB01546 identifier "drugbank:DB01546" assertion.
- drugbank:DB01546 title "Alpha-ethyltryptamine" assertion.
- drugbank:DB01546 drugbank_vocabulary:x-pubchemsubstance pubchem.substance:46507084 assertion.
- drugbank:DB01546 drugbank_vocabulary:x-pubchemcompound pubchem.compound:8367 assertion.
- drugbank:DB01546 drugbank_vocabulary:x-chemspider chemspider:8064 assertion.
- drugbank:DB01546 drugbank_vocabulary:x-cas cas:2235-90-7 assertion.
- drugbank:DB01546 drugbank_vocabulary:drugbank-id "DB01546" assertion.
- drugbank:DB01546 bio2rdf_vocabulary:x-identifiers.org DB01546 assertion.
- drugbank:DB01546 bio2rdf_vocabulary:uri "http://bio2rdf.org/drugbank:DB01546" assertion.
- drugbank:DB01546 bio2rdf_vocabulary:namespace "drugbank" assertion.
- drugbank:DB01546 bio2rdf_vocabulary:identifier "DB01546" assertion.
- drugbank:DB01546 drugbank_vocabulary:x-wikipedia wikipedia:Alpha-ethyltryptamine assertion.
- drugbank:DB01546 drugbank_vocabulary:x-kegg kegg:D04092 assertion.
- drugbank:DB01546 drugbank_vocabulary:x-kegg kegg:C06213 assertion.