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- drugbank:DB05151 type drugbank_vocabulary:Drug assertion.
- drugbank:DB05151 label "TST10088 [drugbank:DB05151]" assertion.
- drugbank:DB05151 seeAlso DB05151 assertion.
- drugbank:DB05151 description "TST10088 is a recombinant variant of a plant toxin belonging to the family of class II ribosome inactivating proteins. These molecules efficiently kill cells by activating preprogrammed death pathways known as apoptosis. TST10088 has been designed and engineered by Twinstrand to contain a peptide switch that is specifically cleaved by the matrix metalloproteinases which are known to be involved in tumor growth and metastasis. Cleavage of the peptide switch activates the prodrug causing ribosomal inactivation and the death of cancerous cells." assertion.
- drugbank:DB05151 identifier "drugbank:DB05151" assertion.
- drugbank:DB05151 title "TST10088" assertion.
- drugbank:DB05151 drugbank_vocabulary:x-cas cas: assertion.
- drugbank:DB05151 drugbank_vocabulary:drugbank-id "DB05151" assertion.
- drugbank:DB05151 bio2rdf_vocabulary:x-identifiers.org DB05151 assertion.
- drugbank:DB05151 bio2rdf_vocabulary:uri "http://bio2rdf.org/drugbank:DB05151" assertion.
- drugbank:DB05151 bio2rdf_vocabulary:namespace "drugbank" assertion.
- drugbank:DB05151 bio2rdf_vocabulary:identifier "DB05151" assertion.