Matches in Nanopublications for { <http://bio2rdf.org/drugbank:DB05448> ?p ?o ?g. }
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- drugbank:DB05448 type drugbank_vocabulary:Drug assertion.
- drugbank:DB05448 label "PX-12 [drugbank:DB05448]" assertion.
- drugbank:DB05448 seeAlso DB05448 assertion.
- drugbank:DB05448 description "PX-12 (1-methylpropyl 2-imidazolyl disulfide) is a small-molecule inhibitor of Trx-1 (thioredoxin-1), stimulates apoptosis, down-regulates HIF-1α and vascular endothelial growth factor (VEGF) and inhibits tumor growth in animal models. Since high levels of Trx-1 have been associated with colorectal, gastric and lung cancers, PX-12 is indicated as a potential cancer treatment in combination with chemotherapy for patients with advanced metastatic cancer. Initial trials correlated doses of Px-12 with increased patient survival." assertion.
- drugbank:DB05448 identifier "drugbank:DB05448" assertion.
- drugbank:DB05448 title "PX-12" assertion.
- drugbank:DB05448 drugbank_vocabulary:x-pubchemcompound pubchem.compound:219104 assertion.
- drugbank:DB05448 drugbank_vocabulary:x-chemspider chemspider:189920 assertion.
- drugbank:DB05448 drugbank_vocabulary:x-cas cas: assertion.
- drugbank:DB05448 drugbank_vocabulary:drugbank-id "DB05448" assertion.
- drugbank:DB05448 bio2rdf_vocabulary:x-identifiers.org DB05448 assertion.
- drugbank:DB05448 bio2rdf_vocabulary:uri "http://bio2rdf.org/drugbank:DB05448" assertion.
- drugbank:DB05448 bio2rdf_vocabulary:namespace "drugbank" assertion.
- drugbank:DB05448 bio2rdf_vocabulary:identifier "DB05448" assertion.