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- drugbank:DB05775 type drugbank_vocabulary:Drug assertion.
- drugbank:DB05775 label "CRx-401 [drugbank:DB05775]" assertion.
- drugbank:DB05775 seeAlso DB05775 assertion.
- drugbank:DB05775 description "CRx-401 is a novel insulin sensitizer designed to provide anti-diabetic activity without promoting weight gain. It consists of a low dose of the analgesic diflunisal in conjunction with a modified-release therapeutic dose of bezafibrate, an anti-cholesterol agent. In third-party clinical studies, the dose of bezafibrate contained in CRx-401 has been observed to have a positive impact on cellular pathways that influence glycemic and lipid profiles, and this dose has proven to be well tolerated in clinical trials. Unlike other NSAIDs, or non-steroidal anti-inflammatory drugs, the dose of diflunisal in CRx-401 has demonstrated in preclinical studies the ability to synergistically enhance the anti-diabetic effects of bezafibrate through novel disease-targeted mechanisms." assertion.
- drugbank:DB05775 identifier "drugbank:DB05775" assertion.
- drugbank:DB05775 title "CRx-401" assertion.
- drugbank:DB05775 drugbank_vocabulary:x-cas cas: assertion.
- drugbank:DB05775 drugbank_vocabulary:drugbank-id "DB05775" assertion.
- drugbank:DB05775 bio2rdf_vocabulary:x-identifiers.org DB05775 assertion.
- drugbank:DB05775 bio2rdf_vocabulary:uri "http://bio2rdf.org/drugbank:DB05775" assertion.
- drugbank:DB05775 bio2rdf_vocabulary:namespace "drugbank" assertion.
- drugbank:DB05775 bio2rdf_vocabulary:identifier "DB05775" assertion.