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- drugbank_resource:DB00333_DB00582 type drugbank_vocabulary:Drug-Drug-Interaction assertion.
- drugbank_resource:DB00333_DB00582 label "DDI between Methadone and Voriconazole - Voriconazole, a strong CYP3A4 inhibitor, may increase the serum concentration of methadone by decreasing its metabolism. Additive QTc prolongation may also occur. Consider alternate therapy or monitor for changes in the therapeutic and adverse effects of methadone if voriconazole is initiated, discontinued or dose changed. [drugbank_resource:DB00333_DB00582]" assertion.
- drugbank_resource:DB00333_DB00582 identifier "drugbank_resource:DB00333_DB00582" assertion.
- drugbank_resource:DB00333_DB00582 title "DDI between Methadone and Voriconazole - Voriconazole, a strong CYP3A4 inhibitor, may increase the serum concentration of methadone by decreasing its metabolism. Additive QTc prolongation may also occur. Consider alternate therapy or monitor for changes in the therapeutic and adverse effects of methadone if voriconazole is initiated, discontinued or dose changed." assertion.