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- drugbank_resource:DB00503_DB00541 type drugbank_vocabulary:Drug-Drug-Interaction assertion.
- drugbank_resource:DB00503_DB00541 label "DDI between Ritonavir and Vincristine - Ritonavir, a strong CYP3A4 and p-glycoprotein inhibitor, may increase the serum concentration of Vincristine by decreasing its metabolism and/or increasing efflux. Consider alternate therapy to avoid Vincristine toxicity. Monitor for changes in the therapeutic and adverse effects of Vincristine if Ritonavir is initiated, discontinued or dose changed. [drugbank_resource:DB00503_DB00541]" assertion.
- drugbank_resource:DB00503_DB00541 identifier "drugbank_resource:DB00503_DB00541" assertion.
- drugbank_resource:DB00503_DB00541 title "DDI between Ritonavir and Vincristine - Ritonavir, a strong CYP3A4 and p-glycoprotein inhibitor, may increase the serum concentration of Vincristine by decreasing its metabolism and/or increasing efflux. Consider alternate therapy to avoid Vincristine toxicity. Monitor for changes in the therapeutic and adverse effects of Vincristine if Ritonavir is initiated, discontinued or dose changed." assertion.