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- NP206319.RAgb_3xCFRZptsjLdKZLO5WC5JPmkkAM5poQ_zLVsGtao130_assertion type Assertion NP206319.RAgb_3xCFRZptsjLdKZLO5WC5JPmkkAM5poQ_zLVsGtao130_head.
- NP206319.RAgb_3xCFRZptsjLdKZLO5WC5JPmkkAM5poQ_zLVsGtao130_assertion wasGeneratedBy ECO_0000203 NP206319.RAgb_3xCFRZptsjLdKZLO5WC5JPmkkAM5poQ_zLVsGtao130_provenance.
- NP206319.RAgb_3xCFRZptsjLdKZLO5WC5JPmkkAM5poQ_zLVsGtao130_assertion wasDerivedFrom befree-20140225 NP206319.RAgb_3xCFRZptsjLdKZLO5WC5JPmkkAM5poQ_zLVsGtao130_provenance.
- NP206319.RAgb_3xCFRZptsjLdKZLO5WC5JPmkkAM5poQ_zLVsGtao130_assertion SIO_000772 16949064 NP206319.RAgb_3xCFRZptsjLdKZLO5WC5JPmkkAM5poQ_zLVsGtao130_provenance.
- NP206319.RAgb_3xCFRZptsjLdKZLO5WC5JPmkkAM5poQ_zLVsGtao130_assertion evidence source_evidence_literature NP206319.RAgb_3xCFRZptsjLdKZLO5WC5JPmkkAM5poQ_zLVsGtao130_provenance.
- NP206319.RAgb_3xCFRZptsjLdKZLO5WC5JPmkkAM5poQ_zLVsGtao130_assertion description "[The initial study found that urine concentrations of the metabolites 1,2-dihydroxy-4-(acetyl) butane (M1) and 1-dihydroxy-2-(N-acetylcysteinyl)-3-butene (M2) and blood concentrations of the hemoglobin adducts N-[2-hydroxy-3-butenyl] valine (HB-Val) and N-[2,3,4-trihydroxy-butyl] valine (THB-Val) constitute excellent biomarkers of exposure, both being highly correlated with BD exposure levels, and that GST genotypes modulate at least one metabolic pathway, but that irreversible genotoxic effects such as chromosome aberrations and HPRT gene mutations are neither associated with BD exposure levels nor with worker genotypes (GST [glutathione-S-transferase]-M1, GSTT1, CYP2E1 (5' promoter), CYP2E1 (intron 6), EH [epoxide hydrolase] 113, EH139, ADH [alcohol dehydrogenase]2 and ADH3).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP206319.RAgb_3xCFRZptsjLdKZLO5WC5JPmkkAM5poQ_zLVsGtao130_provenance.