Matches in Nanopublications for { <http://rdf.disgenet.org/nanopublications.trig#NP444347.RAC9j4STJ32qqiTT1mRFzd1vaqhFNSmH419k3VVw-Gd5E130_assertion> ?p ?o ?g. }
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- NP444347.RAC9j4STJ32qqiTT1mRFzd1vaqhFNSmH419k3VVw-Gd5E130_assertion type Assertion NP444347.RAC9j4STJ32qqiTT1mRFzd1vaqhFNSmH419k3VVw-Gd5E130_head.
- NP444347.RAC9j4STJ32qqiTT1mRFzd1vaqhFNSmH419k3VVw-Gd5E130_assertion wasGeneratedBy ECO_0000203 NP444347.RAC9j4STJ32qqiTT1mRFzd1vaqhFNSmH419k3VVw-Gd5E130_provenance.
- NP444347.RAC9j4STJ32qqiTT1mRFzd1vaqhFNSmH419k3VVw-Gd5E130_assertion wasDerivedFrom befree-20140225 NP444347.RAC9j4STJ32qqiTT1mRFzd1vaqhFNSmH419k3VVw-Gd5E130_provenance.
- NP444347.RAC9j4STJ32qqiTT1mRFzd1vaqhFNSmH419k3VVw-Gd5E130_assertion SIO_000772 8980296 NP444347.RAC9j4STJ32qqiTT1mRFzd1vaqhFNSmH419k3VVw-Gd5E130_provenance.
- NP444347.RAC9j4STJ32qqiTT1mRFzd1vaqhFNSmH419k3VVw-Gd5E130_assertion evidence source_evidence_literature NP444347.RAC9j4STJ32qqiTT1mRFzd1vaqhFNSmH419k3VVw-Gd5E130_provenance.
- NP444347.RAC9j4STJ32qqiTT1mRFzd1vaqhFNSmH419k3VVw-Gd5E130_assertion description "[We conclude: (i) the mitogenic signaling pathway(s) regulating S6 kinase is activated in psoriatic lesions, thus accounting for increased S6 kinase activity in the absence of increased S6 kinase gene or protein expression; (ii) S6 kinase activation in lesional keratinocytes likely occurs in response to EGF receptor stimulation by TGF-alpha and/or amphiregulin, which are known to be elevated in psoriatic lesions; and (iii) keratinocyte as well as T-cell mitogenic signaling pathways are susceptible to inhibition by rapamycin, suggesting that rapamycin may be of therapeutic benefit in the treatment of psoriasis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP444347.RAC9j4STJ32qqiTT1mRFzd1vaqhFNSmH419k3VVw-Gd5E130_provenance.