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- NP718789.RAtKLo-OFlGhdGQVu_VOxrhPv0CuwHXBXylQb5Cb7C8BQ130_assertion type Assertion NP718789.RAtKLo-OFlGhdGQVu_VOxrhPv0CuwHXBXylQb5Cb7C8BQ130_head.
- NP718789.RAtKLo-OFlGhdGQVu_VOxrhPv0CuwHXBXylQb5Cb7C8BQ130_assertion wasGeneratedBy ECO_0000203 NP718789.RAtKLo-OFlGhdGQVu_VOxrhPv0CuwHXBXylQb5Cb7C8BQ130_provenance.
- NP718789.RAtKLo-OFlGhdGQVu_VOxrhPv0CuwHXBXylQb5Cb7C8BQ130_assertion wasDerivedFrom befree-20140225 NP718789.RAtKLo-OFlGhdGQVu_VOxrhPv0CuwHXBXylQb5Cb7C8BQ130_provenance.
- NP718789.RAtKLo-OFlGhdGQVu_VOxrhPv0CuwHXBXylQb5Cb7C8BQ130_assertion SIO_000772 14507635 NP718789.RAtKLo-OFlGhdGQVu_VOxrhPv0CuwHXBXylQb5Cb7C8BQ130_provenance.
- NP718789.RAtKLo-OFlGhdGQVu_VOxrhPv0CuwHXBXylQb5Cb7C8BQ130_assertion evidence source_evidence_literature NP718789.RAtKLo-OFlGhdGQVu_VOxrhPv0CuwHXBXylQb5Cb7C8BQ130_provenance.
- NP718789.RAtKLo-OFlGhdGQVu_VOxrhPv0CuwHXBXylQb5Cb7C8BQ130_assertion description "[Using pancreatic cancer microarrays and immunohistochemistry, we determined that 6% (4 of 46 and 5 of 100 in two independent panels) of pancreatic adenocarcinomas overexpress cyclin E. We identified two potential mechanisms for this overexpression including the amplification/gain of CCNE1 gene copies in the Panc-1 and Su86.86 cell lines and a novel somatic homozygous mutation (H460R, in one of 11 pancreatic cancer xenografts having allelic loss) in FBXW7, which was accompanied by cyclin E overexpression by immunohistochemistry.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP718789.RAtKLo-OFlGhdGQVu_VOxrhPv0CuwHXBXylQb5Cb7C8BQ130_provenance.