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- assertion wasGeneratedBy ECO_0000203 provenance.
- assertion wasDerivedFrom BEFREE provenance.
- assertion SIO_000772 20805990 provenance.
- assertion evidence source_evidence_literature provenance.
- assertion description "[Loss of AP-2alpha expression in metastatic melanoma occurs via a dual mechanism involving binding of CREB to the AP-2alpha promoter and CREB-induced overexpression of another oncogenic transcription factor, E2F-1.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." provenance.