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- assertion wasGeneratedBy ECO_0000203 provenance.
- assertion wasDerivedFrom BEFREE provenance.
- assertion SIO_000772 10721491 provenance.
- assertion evidence source_evidence_literature provenance.
- assertion description "[Since AP-2 also regulates other genes that are involved in the progression of human melanoma such as E-cadherin, MMP-2, p21WAF-1, HER-2, BCL-2, and insulin like growth factor receptor-1, we propose that loss of AP-2 is a crucial event in the development of malignant melanoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." provenance.