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- assertion wasGeneratedBy ECO_0000203 provenance.
- assertion wasDerivedFrom BEFREE provenance.
- assertion SIO_000772 24847881 provenance.
- assertion evidence source_evidence_literature provenance.
- assertion description "[In cancer cell lines, SMYD3-mediated methylation of MAP3K2 at lysine 260 potentiates activation of the Ras/Raf/MEK/ERK signalling module and SMYD3 depletion synergizes with a MEK inhibitor to block Ras-driven tumorigenesis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." provenance.