Matches in Nanopublications for { <http://rdf.disgenet.org/resource/nanopub/NP290026.RAjCnEOoGdtYYpSDhsjRXbounVhf_oSRYMgdSMc38PWTk130_assertion> ?p ?o ?g. }
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- NP290026.RAjCnEOoGdtYYpSDhsjRXbounVhf_oSRYMgdSMc38PWTk130_assertion type Assertion NP290026.RAjCnEOoGdtYYpSDhsjRXbounVhf_oSRYMgdSMc38PWTk130_head.
- NP290026.RAjCnEOoGdtYYpSDhsjRXbounVhf_oSRYMgdSMc38PWTk130_assertion wasGeneratedBy ECO_0000203 NP290026.RAjCnEOoGdtYYpSDhsjRXbounVhf_oSRYMgdSMc38PWTk130_provenance.
- NP290026.RAjCnEOoGdtYYpSDhsjRXbounVhf_oSRYMgdSMc38PWTk130_assertion wasDerivedFrom befree-20150227 NP290026.RAjCnEOoGdtYYpSDhsjRXbounVhf_oSRYMgdSMc38PWTk130_provenance.
- NP290026.RAjCnEOoGdtYYpSDhsjRXbounVhf_oSRYMgdSMc38PWTk130_assertion SIO_000772 14636244 NP290026.RAjCnEOoGdtYYpSDhsjRXbounVhf_oSRYMgdSMc38PWTk130_provenance.
- NP290026.RAjCnEOoGdtYYpSDhsjRXbounVhf_oSRYMgdSMc38PWTk130_assertion evidence source_evidence_literature NP290026.RAjCnEOoGdtYYpSDhsjRXbounVhf_oSRYMgdSMc38PWTk130_provenance.
- NP290026.RAjCnEOoGdtYYpSDhsjRXbounVhf_oSRYMgdSMc38PWTk130_assertion description "[Tumour necrosis factor-alpha production was induced with N-formyl-L-methionyl-L-leucyl-L-phenylalanine (100 nmol/L), lipopolysaccharide (10 micro g/mL), opsonized zymosan (100 micro g/mL) or phorbol 12-myristate 13-acetate (100 nmol/L) for 24 h. We could demonstrate that: (i) there were marked differences in tumour necrosis factor-alpha production only in the differentiated forms of both wild-type and chronic granulomatous disease-mutant cells, while there were no differences in the case of their immature counterparts; (ii) only chronic granulomatous disease-mutant cells retained sensitivity to phorbol 12-myristate 13-acetate both in their granulocytic and monocytic forms, although phorbol 12-myristate 13-acetate responsiveness was a characteristic of both types of immature cells; (iii) the granulocytic form of wild-type cells produced tumour necrosis factor-alpha after opsonized zymosan stimulation, but such a response was not observed in cells originating from the chronic granulomatous disease-mutant cell line; (iv) with the monocytic forms, significantly higher tumour necrosis factor-alpha production could be induced by lipopolysaccharide in the wild-type cells than in the chronic granulomatous disease-mutant cells, although there was no difference in their lipopolysaccharide receptor CD14 expression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP290026.RAjCnEOoGdtYYpSDhsjRXbounVhf_oSRYMgdSMc38PWTk130_provenance.