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- assertion wasGeneratedBy ECO_0000203 provenance.
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- assertion SIO_000772 18351386 provenance.
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- assertion description "[The present observations support that upregulation of HIF-1 alpha and its downstream targets GLUT1 and SDF-1 in colorectal adenomas and carcinomas may be due to hypoxia, in close interaction with an active phosphatidylinositol 3-kinases-AKT-mTOR pathway.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." provenance.