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- assertion wasGeneratedBy ECO_0000203 provenance.
- assertion wasDerivedFrom BEFREE provenance.
- assertion SIO_000772 12804776 provenance.
- assertion evidence source_evidence_literature provenance.
- assertion description "[We reported previously that the hepatitis B virus X (HBx) protein, known to be a causative agent in the formation of HCC, activates insulin-like growth factor II (IGF-II) expression through Sp1 phosphorylation by protein kinase C (PKC) or mitogen-activated protein kinase (MAPK) signaling.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." provenance.