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- assertion wasGeneratedBy ECO_0000203 provenance.
- assertion wasDerivedFrom BEFREE provenance.
- assertion SIO_000772 19805619 provenance.
- assertion evidence source_evidence_literature provenance.
- assertion description "[We show that one such gene, osteopontin (OPN), is a functionally relevant target of the Ser585-survival pathway as shown by siRNA-mediated knockdown of OPN expression that induces cell death in both AML blasts and CD34(+)CD38(-)CD123(+) leukemic progenitors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." provenance.