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- NP567182.RA1K8G3dBJ_50GMsGPvnOMO3PCNgi8TAMREou_tGmwNr4130_assertion type Assertion NP567182.RA1K8G3dBJ_50GMsGPvnOMO3PCNgi8TAMREou_tGmwNr4130_head.
- NP567182.RA1K8G3dBJ_50GMsGPvnOMO3PCNgi8TAMREou_tGmwNr4130_assertion wasGeneratedBy ECO_0000203 NP567182.RA1K8G3dBJ_50GMsGPvnOMO3PCNgi8TAMREou_tGmwNr4130_provenance.
- NP567182.RA1K8G3dBJ_50GMsGPvnOMO3PCNgi8TAMREou_tGmwNr4130_assertion wasDerivedFrom befree-2016 NP567182.RA1K8G3dBJ_50GMsGPvnOMO3PCNgi8TAMREou_tGmwNr4130_provenance.
- NP567182.RA1K8G3dBJ_50GMsGPvnOMO3PCNgi8TAMREou_tGmwNr4130_assertion SIO_000772 16949064 NP567182.RA1K8G3dBJ_50GMsGPvnOMO3PCNgi8TAMREou_tGmwNr4130_provenance.
- NP567182.RA1K8G3dBJ_50GMsGPvnOMO3PCNgi8TAMREou_tGmwNr4130_assertion evidence source_evidence_literature NP567182.RA1K8G3dBJ_50GMsGPvnOMO3PCNgi8TAMREou_tGmwNr4130_provenance.
- NP567182.RA1K8G3dBJ_50GMsGPvnOMO3PCNgi8TAMREou_tGmwNr4130_assertion description "[The initial study found that urine concentrations of the metabolites 1,2-dihydroxy-4-(acetyl) butane (M1) and 1-dihydroxy-2-(N-acetylcysteinyl)-3-butene (M2) and blood concentrations of the hemoglobin adducts N-[2-hydroxy-3-butenyl] valine (HB-Val) and N-[2,3,4-trihydroxy-butyl] valine (THB-Val) constitute excellent biomarkers of exposure, both being highly correlated with BD exposure levels, and that GST genotypes modulate at least one metabolic pathway, but that irreversible genotoxic effects such as chromosome aberrations and HPRT gene mutations are neither associated with BD exposure levels nor with worker genotypes (GST [glutathione-S-transferase]-M1, GSTT1, CYP2E1 (5' promoter), CYP2E1 (intron 6), EH [epoxide hydrolase] 113, EH139, ADH [alcohol dehydrogenase]2 and ADH3).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP567182.RA1K8G3dBJ_50GMsGPvnOMO3PCNgi8TAMREou_tGmwNr4130_provenance.