Matches in Nanopublications for { <http://rdf.disgenet.org/resource/nanopub/NP624097.RAfMY5OAoo5ySbJg1dCs2Y78IS-6b8w5YbUao2DZ3hh4A#assertion> ?p ?o ?g. }
Showing items 1 to 5 of
5
with 100 items per page.
- assertion wasGeneratedBy ECO_0000203 provenance.
- assertion wasDerivedFrom BEFREE provenance.
- assertion SIO_000772 12107246 provenance.
- assertion evidence source_evidence_literature provenance.
- assertion description "[The aim of our study was to identify genetic variants that influence the phenotype of patients with PA. We hypothesized that genetic variants potentially affecting aldosterone production (aldosterone synthase, CYP11B2), renal proximal tubule reabsorption (alpha-adducin), or the mechanisms of counterbalance leading to vasodilatation and sodium excretion (bradykinin B(2)-receptor, B(2)R) could influence the clinical and biochemical characteristics of patients with PA. We studied three polymorphisms of these genes (C-344T of CYP11B2, G460W of alpha-adducin, and C-58T of B(2)R) in 167 primary aldosteronism patients (56 with aldosterone-producing adenoma and 111 with idiopathic hyperaldosteronism).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." provenance.