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- NP775962.RAklF4sLubkYspj50mzdg4O-hJ-pJ8kOetM8M_klJB7p8130_assertion type Assertion NP775962.RAklF4sLubkYspj50mzdg4O-hJ-pJ8kOetM8M_klJB7p8130_head.
- NP775962.RAklF4sLubkYspj50mzdg4O-hJ-pJ8kOetM8M_klJB7p8130_assertion wasGeneratedBy ECO_0000203 NP775962.RAklF4sLubkYspj50mzdg4O-hJ-pJ8kOetM8M_klJB7p8130_provenance.
- NP775962.RAklF4sLubkYspj50mzdg4O-hJ-pJ8kOetM8M_klJB7p8130_assertion wasDerivedFrom befree-20150227 NP775962.RAklF4sLubkYspj50mzdg4O-hJ-pJ8kOetM8M_klJB7p8130_provenance.
- NP775962.RAklF4sLubkYspj50mzdg4O-hJ-pJ8kOetM8M_klJB7p8130_assertion SIO_000772 23075332 NP775962.RAklF4sLubkYspj50mzdg4O-hJ-pJ8kOetM8M_klJB7p8130_provenance.
- NP775962.RAklF4sLubkYspj50mzdg4O-hJ-pJ8kOetM8M_klJB7p8130_assertion evidence source_evidence_literature NP775962.RAklF4sLubkYspj50mzdg4O-hJ-pJ8kOetM8M_klJB7p8130_provenance.
- NP775962.RAklF4sLubkYspj50mzdg4O-hJ-pJ8kOetM8M_klJB7p8130_assertion description "[The present review discusses the substrates of FXIIIa (activated FXIII) involved in thrombosis and wound healing with a particular focus on: (i) the influence of plasma FXIIIa on the formation of stable fibrin clots able to withstand mechanical and enzymatic breakdown through fibrin-fibrin cross-linking and cross-linking of fibrinolysis inhibitors, in particular α2-antiplasmin; (ii) the role of intracellular FXIIIa in clot retraction through cross-linking of platelet cytoskeleton proteins, including actin, myosin, filamin and vinculin; (iii) the role of intracellular FXIIIa in cross-linking the cytoplasmic tails of monocyte AT1Rs (angiotensin type 1 receptors) and potential effects on the development of atherosclerosis; and (iv) the role of FXIIIa on matrix deposition and tissue repair, including cross-linking of extracellular matrix proteins, such as fibronectin, collagen and von Willebrand factor, and the effects on matrix deposition and cell-matrix interactions.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP775962.RAklF4sLubkYspj50mzdg4O-hJ-pJ8kOetM8M_klJB7p8130_provenance.