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- assertion wasGeneratedBy ECO_0000203 provenance.
- assertion wasDerivedFrom BEFREE provenance.
- assertion SIO_000772 14617754 provenance.
- assertion evidence source_evidence_literature provenance.
- assertion description "[In this study we demonstrate that an increase in endogenous tissue-type plasminogen activator (tPA) activity in the perivascular tissue following cerebral ischemia induces opening of the BBB via a mechanism that is independent of both plasminogen (Plg) and MMP-9.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." provenance.