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- assertion wasGeneratedBy ECO_0000203 provenance.
- assertion wasDerivedFrom GAD provenance.
- assertion SIO_000772 19420344 provenance.
- assertion evidence source_evidence_literature provenance.
- assertion description "[Although the PI3K-AKT pathway is known to be dysregulated in retinoblastoma, the low frequency of oncogenic mutations in the AKT1, PIK3CA, and PTEN genes, suggests a different activating mechanism.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." provenance.