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- assertion wasGeneratedBy ECO_0000203 provenance.
- assertion wasDerivedFrom BEFREE provenance.
- assertion SIO_000772 22772468 provenance.
- assertion evidence source_evidence_literature provenance.
- assertion description "[Epidermal cell differentiation and skin tumor suppression were caused by a p53-dependent transcriptional activation of the metalloprotease TACE/ADAM17 (TNF-?-converting enzyme), a previously unknown p53 target gene that was required for NOTCH1 activation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." provenance.