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- _5 wasQuotedFrom 17511588 provenance.
- _5 value "VEGF rapidly activates Rac1 and promotes translocation of Rac1 from the cytosol to the membrane, thereby activating NADPH oxidase in ECs (100). Overexpression of dominant negative N17Rac1 significantly inhibits VEGF-induced ROS production that is involved in VEGFR2 activation, EC migration, and proliferation (100)." provenance.