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- _8 value "As shown in Fig. 1A, all three types of MAPK were activated by TNF in wild-type fibroblasts. By contrast, in Rip-/- cells, the activation of these three types of MAPK was decreased to ~40% for p38, ~70% for ERK and ~60% for JNK (Fig. 1A). The protein levels of p38, ERK, and JNK in Rip-/- cells were similar to those in wild-type cells (Fig. 1A)." provenance.