Matches in Nanopublications for { <http://www.tkuhn.ch/bel2nanopub/RA0dWf9q04tMdvH00LUir4MnrD0APEZQ5b0tpk_jkBPLw#_3> ?p ?o ?g. }
Showing items 1 to 2 of
2
with 100 items per page.
- _3 wasQuotedFrom 14718385 provenance.
- _3 value "Among the strongly induced genes were many involved in protein degradation, including polyubiquitins, Ub fusion proteins, the Ub ligases atrogin-1/MAFbx and MuRF-1, multiple but not all subunits of the 20S proteasome and its 19S regulator, and cathepsin L. Many genes required for ATP production and late steps in glycolysis were down-regulated, as were many transcripts for extracellular matrix proteins. Some genes not previously implicated in muscle atrophy were dramatically up-regulated (lipin, metallothionein, AMP deaminase, RNA helicase-related protein, TG interacting factor) and several growth-related mRNAs were down-regulated (P311, JUN, IGF-1-BP5)" provenance.