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- _5 wasQuotedFrom 10882136 provenance.
- _5 value "This led to the identification of a high molecular weight IkBalpha kinase complex capable of phosphorylating IkBalpha specifically on serines 32 and 36. Subsequently, the same complex was isolated from TNFalpha-induced HeLa cells and found to contain two IkBalpha kinases, designated IKKalpha and IKKbeta (or IKK1 and IKK2). These kinases were cloned and shown to be activated by TNFalpha, IL-1, and PMA." provenance.