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- _4 value "LPS exposure caused a significant increase in pro-inflammatory mediators in the lung tissue (Fig. 3 and Table 2). Although resveratrol did not have a general inhibitory effect on proinflammatory mediators, it did cause a dose-related inhibition of TNF-?, IL-1?, MPO, and CINC-1 levels in the lung tissue (Fig. 3 and Table 2). The positive control, budesonide, caused similar dose-related inhibition of all of the pro-inflammatory proteins increased by LPS treatment (Fig. 3 and Table 2)." provenance.