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- _6 wasQuotedFrom 11050006 provenance.
- _6 value "CKLiK kinase activity was dependent on Ca(++) and calmodulin as analyzed by in vitro phosphorylation of cyclic adenosine monophosphate responsive element modulator (CREM). these results demonstrate that CKLiK is regulated by Ca ++ /calmodulin and that active CKLiK can directly phosphorylate CREM and activate CREB, enhancing its transactivation capacity." provenance.