Matches in Nanopublications for { <http://www.tkuhn.ch/bel2nanopub/RA4pkLHk1Q-Enx_J5js-8Ynj35g8a0LPtrfJx4WV7DLy8#_6> ?p ?o ?g. }
Showing items 1 to 2 of
2
with 100 items per page.
- _6 wasQuotedFrom 17511588 provenance.
- _6 value "HCPTPA overexpression inhibits VEGFinduced VEGFR2 autophosphorylation, EC migration, and proliferation (46). High cell density-enhanced PTP1 (DEP- 1)/CD148 attenuates phosphorylation of VEGFR2 in contact-inhibited confluent ECs (40). A small molecule inhibitor of PTP1B enhances VEGF-induced VEGFR2 autophosphoryla- tion, migration, and proliferation of EC, as well as neovascularization in a mouse matrigel model (92). Angiopoietin-1 stimulates association of SHP-2 to the phosphorylated Tie-2 receptor (47), which in turn inhibits PI3 kinase-dependent signaling pathways leading to EC migration." provenance.