Matches in Nanopublications for { <http://www.tkuhn.ch/bel2nanopub/RA4yUCqmlZZ0-ltm6N-hGsDz3EtMCgYMruaLkeyqa2u0I#_5> ?p ?o ?g. }
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- _5 wasQuotedFrom 10194465 provenance.
- _5 value "Phosphotyrosine at site 960 of the b subunit just inside the membrane creates an NPXpY-recognition motif for the PTB domain of the IRS proteins. Modification of this tyrosine completely inhibits subsequent phosphorylation of IRS-1 and other insulin receptor substrates and leads to loss of most insulin-dependent biological actions" provenance.