Matches in Nanopublications for { <http://www.tkuhn.ch/bel2nanopub/RA5NiM46sIf9T6VL5dIQubmuVx-RFeZsQV2Q-7sa9DGOM#_4> ?p ?o ?g. }
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- _4 wasQuotedFrom 11877431 provenance.
- _4 value "Here we report that PLC stimulation by the M(3) mAChR expressed in HEK-293 cells also involves, in part, similar mechanisms. M(3) mAChR-mediated PLC stimulation and [Ca(2+)](i) increase were reduced by 2',5'-dideoxyadenosine (dd-Ado), a direct adenylyl cyclase inhibitor. On the other hand, overexpression of Galpha(s) or Epac1, a cyclic AMP-regulated guanine nucleotide exchange factor for Rap GTPases, enhanced M(3) mAChR-mediated PLC stimulation." provenance.