Matches in Nanopublications for { <http://www.tkuhn.ch/bel2nanopub/RA5fc7umMiJNPqQUpM9jLfoxmqtEBoSUMLv8Wpjca9NLE#_3> ?p ?o ?g. }
Showing items 1 to 2 of
2
with 100 items per page.
- _3 wasQuotedFrom 17187782 provenance.
- _3 value "Upon hypoxia, the expression of HIF-1alpha and VEGF gene was induced. The result of Western blotting showed that the expression of alpha-SMA was increased by hypoxic stimulation. Furthermore, the expression of MMP-2 and TIMP-1 genes was increased. Hypoxia also elevated the protein expression of the collagen type I in LX-2 cells. The analysis of TGF-beta/Smad signaling pathway showed that hypoxia potentiated the expression of TGF-beta1 and the phosphorylation status of Smad2. See Table 2 for results of microarray experiment." provenance.