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- _4 wasQuotedFrom 17967972 provenance.
- _4 value "endothelial cells cocultured with smooth muscle cells upregulated CD40 expression in response to cyclic stretch through a transforming growth factor-beta1/activin-receptor-like kinase-1 (Alk-1)-dependent mechanism...TGF-?1 activity was blocked with a neutralizing antibody, and this prevented the stretch-induced increase in CD40 mRNA and protein outright...disturbance of Alk-1 function by the employment of soluble Alk-1 receptor molecules blocked the increase in CD40 protein [western and rtpcr]" provenance.