Matches in Nanopublications for { <http://www.tkuhn.ch/bel2nanopub/RA62x0YIGwKdsfzcxOn2pF74GC-K0fxwae5BurGQtCP-s#_6> ?p ?o ?g. }
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- _6 wasQuotedFrom 14561188 provenance.
- _6 value "activation of PPARa represses p65 transactivation of the human IL-6 promoter. This antagonism occurs in a reciprocal manner, since cotransfection of increasing amounts of p65 led to a dosedependent inhibition of a PPARa-mediated activation of a PPAR response element-driven promoter. Transrepression occurs through direct protein-protein interactions between PPARa and the p65 subunit of NF-kB [28]." provenance.